Solubility of HPMC in Organic Solvents
October 29th 2024
The light transmittance of hydroxypropyl methylcellulose is mainly affected by the following points:
1. The quality of raw materials.
Second, the effect of alkalization.
3. Process ratio
4. Proportion of solvent
5. The effect of neutralization
Some products are cloudy like milk after they are dissolved, some are milky white, some are yellowish, and some are clear and transparent… To solve the problem, adjust from the following points. Sometimes acetic acid can seriously affect the light transmittance. It is best to use acetic acid after dilution. The biggest influence is whether the reaction is stirred evenly and whether the system ratio is stable (some materials have moisture and the content is unstable, such as the solvent used for recycling). In fact, many factors are affecting. If the equipment is stable and the operators are well trained, the production should be very stable. The light transmittance will not exceed the range of ±2%, and the substitution uniformity of the substituent groups must be well controlled. Instead of uniformity, light transmittance would definitely be fine.
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