Unstable viscosity after HPMC dissolution

Reason:

  • The water temperature fluctuated greatly during dissolution, resulting in uneven dissolution of HPMC.
  • Insufficient stirring time or too short resting time, HPMC is not completely dissolved.
  • HPMC batch differences or improper storage conditions affect viscosity stability.

Solution:

  • Maintain a constant water temperature during the dissolution process, stir and leave it for enough time (usually 2-4 hours) waiting for HPMC to fully dissolve.
  • Stir again after dissolving to ensure uniform viscosity.
  • Regularly test the batch quality of HPMC to ensure consistency.

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